Clonazepam vs. Xanax: Differences, dosage, and side effects

Alprazolam ( Xanax ) and clonazepam ( Klonopin ) are both medications that affect a person ’ second central anxious arrangement ( CNS ) by slowing it down. They belong to a class of drugs called benzodiazepines. Doctors tend to prescribe these to treat anxiety and panic disorders. The most coarse use of alprazolam is as an antianxiety medicine. pharmaceutical company Upjohn created this drug in 1969, and doctors now write more than 50 million prescriptions for Xanax each year. Clonazepam can help treat capture disorders, among other things. It is an anticonvulsant and anticonvulsant medicine. Doctors may besides prescribe clonazepam for panic disorder.

alprazolam and clonazepam both affect the CNS and have the potential for pervert, with some people becoming pendent on them .

What do people use them for?

alprazolam is a utilitarian medication for people who experience panic attacks. The drug helps relieve the symptoms and reduce the frequency of attacks. Some doctors prescribe alprazolam for natural depression, but there is limited evidence to suggest that it is effective unless the person besides has anxiety. Clonazepam is besides a benzodiazepine. Doctors use it to treat seizure disorders in both adults and children. It can help address chemical imbalances in the brain and reduce the number of panic attacks. Taking clonazepam increases a person ’ sulfur levels of gamma-aminobutyric acid ( GABA ), which is a chemical that sends signals around the CNS. A miss of GABA action can cause people to become excitable and may lead to panic attacks or seizures. Having more gamma aminobutyric acid action in the consistency helps reduce instances of panic attacks and seizures .

How do they differ?

At first glance, Xanax and clonazepam are very similar. Both medications are benzodiazepines, CNS depressants, and ways of treating anxiety or panic attacks. Both are curtly acting drugs, but clonazepam stays in the torso for longer than alprazolam. The half life of Xanax is 6–25 hours, while for clonazepam, it is 22–54 hours. Clonazepam can besides treat seizures, whereas Xanax does not. Both drugs have their different off-label uses, which the sections below will look at in more contingent.

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Dosage comparison

Dosages normally differ depending on the individual and the discipline that a repair is trying to treat .

Clonazepam dosage

For panic and anxiety, the dose for adults is 0.25 milligrams ( magnesium ) doubly per day. A doctor can increase the dose in increments of 0.125 mg to 0.25 milligram every 3 days until the panic is under control. however, the maximum dose does not normally exceed 4 milligram per day. For seizures, the dose for adults is 0.5 magnesium three times per day. A repair can increase the dose in increments of 0.5 mg to 1 magnesium until the seizures are under dominance. The maximum dose should not exceed 20 magnesium per day .

Xanax dosage

For anxiety disorders, the dose for adults typically starts at 0.25 magnesium to 0.5 mg three times per day. A doctor may incrementally increase the dose to maximize the effect. however, the maximum dose does not normally exceed 4 milligram per day. For panic disorders, the compulsory venereal disease of Xanax may exceed 4 milligram per day. Controlled trials involving 1,700 people found that Xanax worked for panic perturb when participants received 1–10 mg per day .

Changing dosage

Whether prescribing clonazepam or alprazolam, a repair will normally start at the lowest potential dose, regularly reassess the dose, and consider reducing it, for model, if panic attacks stop. If a doctor advises reducing the dose, they must ensure that a person does this lento. If a person stops taking either drug abruptly, it could result in withdrawal symptoms. Both Xanax and clonazepam typically begin taking consequence after a few hours or days of starting the medicine. A venereal disease of Xanax will affect a person for a few hours. A dose of clonazepam can last around three times longer .

Benzodiazepine dependence

long-run function of benzodiazepines can lead to dependence on these drugs. addiction can begin after using the drugs for adenine little as 1 month. As alprazolam remains in the body for less time than clonazepam, it may carry a higher risk of overuse or misuse, which may lead to dependence. It is critical that a person does not stop taking either drug on the spur of the moment. Doing so can lead to adverse effects, such as life threaten seizures, deoxyadenosine monophosphate well as withdrawal symptoms. A sophisticate or pharmacist should cautiously monitor how a person uses benzodiazepines to manage the risk of addiction .

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Forms comparison

Clonazepam comes in the form of an oral pad that a person swallows. There is besides a version that dissolves in the sass. alprazolam is available in immediate-release and extended-release oral tablets, vitamin a well as an oral solution.

Side effects

These drugs can have a act of adverse effects. The sections below will look at these in more contingent .


Some of the more common side effects of clonazepam include :

  • drowsiness
  • shaky movements and unsteady gait
  • dizziness
  • depression
  • fatigue
  • memory problems
  • constipation or diarrhea
  • nausea

If any of these side effects develop, a person should talk to their repair. Some rare and more severe side effects of clonazepam include :

  • depressed mood or suicidal thoughts
  • seizures, especially if a person stops taking the drug suddenly
  • hallucinations
  • mood and behavioral changes
  • sweating
  • abnormal eye movements
  • anxiety
  • difficulty speaking
  • insomnia
  • excessive bleeding and bruising, from reduced platelets in the blood
  • menstrual problems
  • difficulty urinating

If any of these slope effects develop, a person needs immediate medical attention .


Some of the more common side effects of Xanax include :

  • drowsiness and fatigue
  • lightheadedness
  • headaches
  • nausea
  • dry mouth
  • irritability
  • becoming talkative
  • forgetfulness or difficulty concentrating
  • difficulty passing urine
  • constipation
  • joint pain
  • changes in appetite
  • changes in weight
  • sexual dysfunction

If any of these side effects develop, a person should make an appointment to see their doctor. Some rare and more severe side effects of Xanax include :

  • yellowing of the skin or eyes
  • difficulty speaking
  • poor coordination and balance
  • seizures
  • mood changes
  • hallucinations
  • confusion or memory problems
  • depression or suicidal thoughts
  • a severe rash

If any of these side effects develop, a person needs immediate aesculapian attention. As both Xanax and clonazepam may cause sleepiness and poor coordination, people taking these drugs should be cautious about driving and operating machinery. With either drug, a severe allergic reaction is unlikely. however, if a person develops any symptoms of a reaction — such as a rash, difficulty breathe, itching, or swelling — they need emergency help.

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People taking alprazolam or clonazepam should not mix them with alcohol or opioid medication. Doing so can cause dangerous side effects that could be fatal. other CNS depressants can besides interact with Xanax or clonazepam and change the way they work. such changes can besides lead to severe side effects. Some other CNS depressants include :

  • cannabis
  • antihistamines
  • sedatives and sleeping pills
  • tranquilizers
  • mood stabilizers
  • muscle relaxants
  • seizure medications
  • pain medications

Before starting to take a new medication, a person should tell their doctor or pharmacist about any other drugs that they are taking or planning to take.

Off-label uses

Off-label uses are uses that are not indicated on the Food and Drug Administration ( FDA ) -approved packaging but for which a doctor of the church might still prescribe the drug. Some off-label uses for Xanax include the follow :

  • irritable bowel syndrome
  • essential tremor
  • ringing in the ears
  • depression
  • agoraphobia, or a fear of open spaces
  • premenstrual syndrome

Some off-label uses for clonazepam include the following :

  • burning mouth syndrome
  • essential tremor
  • depression
  • multiple sclerosis
  • periodic limb movement disorder
  • restless legs syndrome
  • ringing in the ears
  • Tourette’s syndrome
  • vertigo
  • West syndrome

Which is the best one to use?

Although clonazepam and Xanax are like types of drug, there are times when one might be better to use than the other. alprazolam is not a capture medication. consequently, a person trying to control and treat seizures may find clonazepam more utilitarian. People with anxiety disorders should make an date with their doctor to discuss the respective discussion options and the pros and cons of each.

The doctor will ask about the person ’ mho symptoms and medical history. They will consider any current medicine the individual is taking before advising which prescription is most suitable. Some people ’ south bodies react badly to particular medications, or the drug may be ineffective. If this is the case, a person should talk to their doctor, who can make an alternative recommendation .

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