“ This is the first analyze to show that serum and urine biomarkers can efficaciously detect improvements in a comprehensive spectrum of validate clinical consequence measures of annoyance, routine and quality of life in patients receiving Cosamin ASU, ” said Dr. James Cook, principle study research worker and Director, University of Missouri Comparative Orthopaedic Laboratory, Mizzou BioJoint Center .
Cosamin ASU is a combination of glucosamine hydrochloride ( FCHG49® ), chondroitin sulfate ( TRH122® ), avocado/soybean unsaponifiables ( NMX1000® ASU ), 3-O-acetyl-11-keto-boswellic acid ( AKBA ) ( QUIKLOX™ ), and decaffeinated green tea extract .
Throughout the study time period, investigators collected, processed and analyzed blood and urine from five patients using a multiplexed proprietary empanel of biomarkers. At each of the five clinic visits throughout the test, SF-36, KOOS, WOMAC, and IKDC subject and examination questionnaires were administered according to published protocols.
All serum and urine biomarkers evaluated showed measured changes in concentrations over the study period with statistically meaning ( p < 0.05 ) differences noted for serum PGE2, MMP1, GRO, IL8, and high-sensitivity C-reactive protein ( hsCRP ) and urine PGE2, MMP2, MMP3, GRO and IL8 ; markers associated with joint discomfort and cartilage dislocation .
`` This comprehensive fly analysis provides us with extra defend of the efficacy of Cosamin ASU for promoting joint health, '' said Dr. Brian Cornblatt, Medical Director of Nutramax Laboratories Consumer Care, Inc. `` Using biomarkers to assess our products in the human clinical trial setting allows us to translate our in vitro findings. For years we have studied the effects of our novel formulations on well-recognized weave culture models. To see these lapp biomarkers associated with joint discomfort and cartilage breakdown decrease significantly in a clinical trial put is reassuring as we carefully seek to develop our products backed by sound and robust skill. ”
subsequent research plans include a multi-center, placebo-controlled clinical discipline aimed at far bridging clinical assessments of Cosamin ASU with validate biomarkers.
About the Nutramax Laboratories Family of Companies:
Since 1992, Christian-based Nutramax Laboratories has been developing products for people and their pets. Nutramax Laboratories Consumer Care, Inc., located in Edgewood, Maryland, focuses on researching and developing high choice products to promote consumer health. Located in Lancaster, South Carolina, Nutramax Laboratories Veterinary Sciences, Inc. researches and develops high quality products to support animal health. Nutramax Manufacturing, Inc. manufactures products in both the Maryland and South Carolina locations.
Cosamin® joint health supplements, including the original Cosamin®DS and advanced formula Cosamin®ASU, are available at retailers across the U.S. to help back and promote roast health .
SOURCE Nutramax Laboratories Consumer Care, Inc .
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