Doxycycline Monohydrate vs Hyclate: Main Differences and Similarities

Doxycycline monohydrate and doxycycline hyclate both belong to the group of antibiotics called tetracyclines. They work by blocking protein deduction which prevents the growth of bacteria. consequently, these antibiotics are considered bacteriostatic. The merely difference between doxycycline monohydrate and doxycycline hyclate is in their salt form. We ’ ll discuss their similarities and differences hera .

Doxycycline Monohydrate

Doxycycline monohydrate ( Monodox ) is an antibiotic that belongs to the tetracycline group. It is used in the discussion of respiratory tract infection including pneumonia and chronic bronchitis, pelvic inflammatory disease, urinary tract infection, chlamydia, syphilis, mycoplasma, traveler ’ south diarrhea, cholera, malaria, blight, melioidosis, brucellosis, Q fever and early infections .

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Doxycycline monohydrate ( What is Doxycycline Monohydrate ? ) is the less soluble salt form of doxycycline. consequently, it may have less gastrointestinal side effects associated with it .
Doxycycline monohydrate can be purchased as a brand or generic drug. It is available as an oral encapsulate in varying strengths. Doxycycline monohydrate use is contraindicated in pregnancy, children, systemic lupus erythematosus ( SLE ), and porphyria .

Doxycycline Hyclate

Doxycycline hyclate ( Doryx, Vibramycin ) is an antibiotic that besides belongs to the tetracyclines. It is used in treating a wide-eyed variety of infections including respiratory tract infection including pneumonia and chronic bronchitis, pelvic inflammatory disease, urinary tract infection, syphilis, chlamydia, mycoplasma, cholera, malaria, and other diseases .
Doxycycline hyclate ( What is Doxycycline Hyclate ? ) is considered the more soluble strategic arms limitation talks imprint of doxycycline. It has besides been the least expensive of the two strategic arms limitation talks forms .
Doxycycline hyclate can be purchased as a post or generic drug and is normally taken as an oral condensation. Its use is contraindicated in pregnancy, children, porphyria, and systemic lupus erythematosus ( SLE ).

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Doxycycline Monohydrate vs Doxycycline Hyclate

Doxycycline monohydrate and doxycycline hyclate are exchangeable drugs that differ only in their salt form. Their features can be found in the comparison postpone below .

Doxycycline monohydrate
Doxycycline hyclate

Prescribed For

  • Respiratory tract infection including pneumonia and chronic bronchitis.
  • Urinary tract infections
  • Syphilis
  • Chlamydia
  • Pelvic inflammatory disease
  • Brucellosis
  • Plague
  • Q fever
  • Malaria
  • Traveller’s diarrhea
  • Cholera
  • Rickettsia
  • Respiratory tract infection including pneumonia and chronic bronchitis.
  • Urinary tract infections
  • Syphilis
  • Chlamydia
  • Pelvic inflammatory disease
  • Brucellosis
  • Plague
  • Q fever
  • Malaria
  • Traveller’s diarrhea
  • Cholera
  • Rickettsia

Drug Classification

  • Tetracycline
  • Tetracycline

Manufacturer

  • Generic
  • Generic

Common Side Effects

  • Headache
  • Rash
  • Diarrhea
  • Nausea
  • Vomiting
  • Sore gums
  • Muscle pain
  • Photosensitivity
  • Visual disturbance
  • Headache
  • Rash
  • Diarrhea
  • Nausea
  • Vomiting
  • Sore gums
  • Muscle pain
  • Photosensitivity
  • Visual disturbance

Is there a generic?

  • Doxycycline monohydrate is the generic name.
  • Doxycycline hyclate is the generic name.
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Is it covered by insurance?

  • Varies according to your provider
  • Varies according to your provider

Dosage Forms

  • Oral capsule
  • Oral capsule, delayed release
  • Oral tablet
  • Oral capsule
  • Oral capsule, extended release
  • Oral powder for suspension
  • Oral tablet

Average Cash Price

  • $75 for 60, 50 mg Mondoxyne NL oral capsule
  • $1,341 for 60, 100 mg Morgidox oral capsules

SingleCare Discount Price

  • Doxycycline monohydrate Price
  • Doxycycline hyclate Price

Drug Interactions

  • Amoxicillin
  • Ampicillin
  • Lomitapide
  • Tretinoin
  • Acitretin
  • Aluminium hydroxide
  • Calcium acetate
  • Calcium chloride
  • Calcium gluconate
  • Calcium citrate
  • Fentanyl
  • Ferrous fumarate
  • Ferrous gluconate
  • Ferrous sulphate
  • Magnesium oxide
  • Magnesium sulfate
  • Magnesium citrate
  • Pancuronium
  • Rapacuronium
  • Sodium bicarbonate
  • Sodium citrate
  • Warfarin
  • Amoxicillin
  • Ampicillin
  • Lomitapide
  • Tretinoin
  • Acitretin
  • Aluminium hydroxide
  • Calcium acetate
  • Calcium chloride
  • Calcium gluconate
  • Calcium citrate
  • Fentanyl
  • Ferrous fumarate
  • Ferrous gluconate
  • Ferrous sulphate
  • Magnesium oxide
  • Magnesium sulfate
  • Magnesium citrate
  • Pancuronium
  • Rapacuronium
  • Sodium bicarbonate
  • Sodium citrate
  • Warfarin

Can I use while planning pregnancy, pregnant, or breastfeeding?

  • Doxycycline monohydrate is in pregnancy category D. it should not be taken during pregnancy. Consult a doctor regarding steps to take while planning pregnancy or breastfeeding.
  • Doxycycline hyclate is in pregnancy category D. it should not be taken during pregnancy. Consult a doctor regarding steps to take while planning pregnancy or breastfeeding.
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Summary

Doxycycline monohydrate and doxycycline hyclate are antibiotics used in the treatment of a wide range of infections. Both forms of doxycycline are effective against a broad range of gram-negative and gram-positive bacteria. They work by preventing the growth of bacteria and blocking bacterial protein deduction .
Doxycycline monohydrate and doxycycline hyclate disagree only in their salt form- monohydrate and hyclate. Hyclate has greater solubility than monohydrate. however, the monohydrate shape may be more tolerable. Regardless of their solvability differences, both forms are effective at treating infections .
Both forms of doxycycline should not bused in fraught and breastfeed women. It is besides not advised to give doxycycline to children under 8 years of old .
Doxycycline monohydrate and doxycycline hyclate have significant interactions with other drugs and should not be administered with them.

The data provided here is meant for educational purpose and should be evaluated by your doctor to find the best treatment for you .